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testosterone propionate vs enanthate bodybuilding motivation 

testosterone propionate vs enanthate

Marked antagonism with glucocorticosteroids (GCS) (due to competition on the level of communication with the receptors). Increases contractility of the myometrium, stimulating the release of IL-8 in horiodetsidualnyh cells, increasing the sensitivity of the myometrium to prostaglandins (to enhance the effect used in combination with a synthetic prostaglandin analog). As testosterone propionate vs enanthate a result of the drug takes place decidua desquamation and removal of the ovum.

After a single oral dose of 600 mg maximum concentration of 1.98 mg / l is reached after 1.30 hours. The absolute bioavailability is 69%.
In the mifepristone plasma 98% protein bound:. Albumin and alpha-1-acid glycoprotein
After removing first phase distribution is slow, decreases the concentration of 2-fold between 12-72 hours, and then more quickly. The half-life is 18 hours.

Indications for use of
medical termination of intrauterine pregnancy in the early stages (up to 42 days of amenorrhea). Training and induction of labor at term.

Contraindications
Presence in hypersensitivity history to mifepristone, adrenal insufficiency and long-term glucocorticoid therapy, acute or chronic renal and / or hepatic impairment, porphyria, uterine fibroids, the presence of uterine scar, anemia, disorders of hemostasis (including previous treatment with anticoagulants), inflammatory diseases of the female sexual organs, the presence of severe extragenital pathology. Do not use smoking women older than 35 years (without prior consultation of the therapist). For the medical termination of pregnancy: Suspected ectopic pregnancy.Pregnancy is not confirmed by clinical studies, exceeding by due date 42 days after the cessation of menstruation, which arose during treatment with intrauterine contraception, or after the cancellation of hormonal contraception. For the training and induction of labor: . Preeclampsia severe, preeclampsia, eclampsia, preterm or post-term pregnancy with caution the drug is prescribed for chronic obstructive lung disease (including asthma), severe hypertension, testosterone propionate vs enanthate heart rhythm disturbances and heart failure.

 

Dosing and Administration The drug is to be applied to establishments that have appropriately trained medical personnel and necessary equipment. For medical abortion: 600 mg of mifepristone (three 200 mg tablets) taken orally once in the presence of a doctor. The patient should be under medical supervision for at least 2 hours after application. After 36-48 hours after ingestion Mifegin patient should come to the ultrasound control. After 8-14 days, again carried out a clinical examination and ultrasound control, as well as determine the level of beta-human chorionic hormone to confirm that there was a miscarriage.In the absence of effect of the drug on day 14 (incomplete abortion or ongoing pregnancy) conducted vakuumaspiratsiyu with subsequent histological examination of the aspirate. For preparation and induction of labor: single 200 mg of mifepristone (one tablet) per day orally in the presence of a doctor. After 24 hours, a second receiving 200 mg. After 48-72 hours assesses the state of the birth canal, and, if necessary, be appointed by prostaglandins or oxytocin.

Side effects A. Related treatment procedure: bleeding from the genital tract. Pain in the lower abdomen. Exacerbation of inflammatory processes of the uterus and appendages. B. Related Mifegin reception.The feeling of discomfort in the abdomen, weakness, headache, nausea and vomiting, dizziness, hyperthermia.

Overdosing
mifepristone at doses up to 2 g does not cause unwanted reactions. In cases of overdose adrenal insufficiency may occur.

Interactions with other drugs and other forms of interaction
Avoid the use of non-steroidal anti-inflammatory drugs.

Cautions
Patients should be informed that if the effect on the 10-14 day of the drug is not available (incomplete abortion or ongoing pregnancy), pregnancy, be sure to interrupt the other way, because it is possible the formation of congenital malformations in the fetus.
Use of the testosterone propionate vs enanthate drug requires prevention of Rhesus alloimmunization and other general activities related to abortion. bodybuilding supplements tretizen 20 bodybuilding ireland

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